Version: (using KDE 4.2.2) Installed from: Debian testing/unstable Packages leaving System settings → Mouse and Keyboard → Standard Keyboard Shortcuts withour saving (Cancel or Discard) messes up the list of shortcuts (doubling the entries etc.) Cancel does even get the icon-bar and the settings out of sync, by not changing the settings-dialog but changing the icon.
I cannot reproduce the first described bug. The second one is bug 163693. *** This bug has been marked as a duplicate of bug 163693 ***