How to reproduce:
- add a new profile
- choose appearance 'black on white'
- select e.g. ubuntu monospace font (or hack or noto) as terminal font
- put a checkmark into 'draw intense colors in bold font'

Result:
The first profile draws fonts (e.g man man) in bold
Switching to the second profile ignores the bold setting
Kill konsole
start again
now the second profile works (sometimes) with bold fonts

Add a new profile, same problem as above...

The things i see in the .profile files is a a difference in the font-parameter:
the working profile is
Font=Liberation Mono,11,-1,5,50,0,0,0,0,0 
the -sometimes- working second profile has
Font=Ubuntu Mono,11,-1,5,50,0,0,0,0,0,Regular

but... deleting the 'regular' addition does not solve the problem

At the moment, i have two profiles with the settings as above (with 'regular') and it is working.
But the problem should be fixed